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1. 1.

   Which of the following is a natural emulsifying agent obtained from vegetable sources?

   Gelatin Acacia Egg yolk Bentonite
2. 2.

   BCS Class II drugs possess which of the following characteristics?

   High solubility, High permeability Low solubility, High permeability High solubility, Low permeability Low solubility, Low permeability
3. 3.

   The HLB value range for oil-in-water (O/W) emulsifying agents is generally:

   1 to 3 3 to 6 7 to 9 8 to 16
4. 4.

   Which equipment works on the principle of impact and attrition?

   Hammer mill Ball mill Fluid energy mill Edge runner mill
5. 5.

   Dextrose injection IP is sterilized by which method?

   Autoclaving Dry heat sterilization Filtration Gas sterilization
6. 6.

   The disintegration time for hard gelatin capsules as per IP is not more than:

   15 minutes 30 minutes 60 minutes 5 minutes
7. 7.

   Which tablet excipient acts as a superdisintegrant?

   Lactose Microcrystalline cellulose Sodium starch glycolate Magnesium stearate
8. 8.

   The coating material widely used for enteric coating of tablets is:

   Hydroxypropyl methylcellulose Ethyl cellulose Cellulose acetate phthalate Polyethylene glycol
9. 9.

   The principle of freeze drying (lyophilization) is based on:

   Evaporation Sublimation Condensation Desiccation
10. 10.

    Pyrogen test in animals is performed on which animal?

    Guinea pig Rabbit Albino rat Mouse
11. 11.

    Schick test is used for the diagnosis of:

    Tuberculosis Diphtheria Typhoid Syphilis
12. 12.

    Widal test is used to diagnose:

    Typhoid fever Malaria Cholera Tuberculosis
13. 13.

    Which instrument is used to determine the surface tension of liquids?

    Viscometer Stalagmometer Pycnometer Refractometer
14. 14.

    Thixotropy is defined as:

    Reversible gel-to-sol transformation Irreversible viscosity increase Constant viscosity under shear Increase in volume upon shearing
15. 15.

    LAL test (Limulus Amebocyte Lysate) is used to detect:

    Bacterial endotoxins Fungal spores Heavy metals Particulate matter
16. 16.

    Which propellant is commonly used in metered dose inhalers (MDIs)?

    Chlorofluorocarbon (CFC-11) Hydrofluoroalkane (HFA) Methane Nitrous oxide
17. 17.

    The bloom strength of gelatin used in capsule shell manufacturing ranges between:

    50 to 100 g 150 to 250 g 300 to 400 g 500 to 600 g
18. 18.

    Non-ideal behavior of powders like dilatancy is characterized by:

    Decrease in viscosity Increase in volume under stress Constant flow property High elasticity
19. 19.

    Type I glass is chemically known as:

    Soda lime glass Borosilicate glass Treated soda lime glass General purpose soda glass
20. 20.

    A suppository base containing cocoa butter exhibits which property?

    High water solubility Polymorphism High saponification value Resistance to oxidation
21. 21.

    Which drug is considered the drug of choice for anaphylactic shock?

    Adrenaline Atropine Hydrocortisone Salbutamol
22. 22.

    Morphine causes analgesia primarily by acting on which opioid receptors?

    Mu (μ) receptors Kappa (κ) receptors Delta (δ) receptors NOP receptors
23. 23.

    Which antihypertensive drug is contraindicated in pregnant women due to teratogenicity?

    Methyldopa Labetalol Enalapril Hydralazine
24. 24.

    The antidote for paracetamol poisoning is:

    N-Acetylcysteine Atropine Naloxone Flumazenil
25. 25.

    Mechanism of action of penicillin is inhibition of:

    Bacterial cell wall synthesis Protein synthesis at 30S ribosome DNA gyrase Folic acid synthesis
26. 26.

    Which diuretic acts on the thick ascending limb of the Loop of Henle?

    Hydrochlorothiazide Spironolactone Furosemide Acetazolamide
27. 27.

    Flumazenil is a specific antagonist for toxicity caused by:

    Barbiturates Benzodiazepines Opioids Organophosphates
28. 28.

    Grey baby syndrome is a well-known adverse effect of:

    Tetracycline Chloramphenicol Gentamicin Erythromycin
29. 29.

    Ototoxicity and nephrotoxicity are major side effects of which class of antibiotics?

    Macrolides Aminoglycosides Fluoroquinolones Cephalosporins
30. 30.

    Which H2-receptor antagonist is known to inhibit hepatic cytochrome P450 enzymes?

    Ranitidine Famotidine Cimetidine Nizatidine
31. 31.

    Proton pump inhibitors (PPIs) act by irreversibly inhibiting:

    H+/K+ ATPase Na+/K+ ATPase Histamine H2 receptor Gastrin receptor
32. 32.

    Disulfiram is used in the treatment of:

    Alcohol addiction Opioid dependence Nicotine addiction Barbiturate toxicity
33. 33.

    Sublingual administration of nitroglycerin is preferred in angina because it:

    Has slow absorption Bypasses first-pass metabolism Increases renal excretion Reduces gastric irritation
34. 34.

    Aspirin exerts its antiplatelet effect by irreversibly inhibiting:

    Cyclooxygenase-1 (COX-1) Phosphodiesterase-3 Lipoxygenase Thromboxane synthase
35. 35.

    Which antidiabetic drug belongs to the class of Biguanides?

    Glibenclamide Pioglitazone Metformin Acarbose
36. 36.

    Cinchonism is a toxic manifestation of which drug?

    Quinine Chloroquine Primaquine Amodiaquine
37. 37.

    Atropine is chemically classified as an alkaloid of which type?

    Tropane alkaloid Indole alkaloid Isoquinoline alkaloid Quinoline alkaloid
38. 38.

    Which beta-blocker possesses selective Beta-1 cardioselectivity?

    Propranolol Atenolol Timolol Carvedilol
39. 39.

    Warfarin monitoring is routinely performed using which test?

    aPTT INR (Prothrombin Time) Bleeding time Clotting time
40. 40.

    Rifampicin colors urine and body secretions in which color?

    Blue Orange-red Green Dark brown
41. 41.

    Which titration method uses potassium chromate as an indicator?

    Mohr’s method Volhard’s method Fajans’ method Kjeldahl method
42. 42.

    Karl Fischer reagent is primarily used for the estimation of:

    Water / Moisture content Nitrogen content Sulfate impurities Alcohol content
43. 43.

    The chemical structure of Penicillin consists of a fused ring system of:

    Beta-lactam and Thiazolidine Beta-lactam and Morpholine Imidazole and Thiazole Pyridine and Piperidine
44. 44.

    Which heterocyclic ring is present in the structure of Imidazole?

    Five-membered ring with two nitrogen atoms Six-membered ring with two nitrogen atoms Five-membered ring with one nitrogen atom Six-membered ring with one nitrogen atom
45. 45.

    Indicate the limit test principle for Iron: reaction between iron and thioglycolic acid in the presence of:

    Ammonium chloride Ammonia solution Hydrochloric acid Sodium hydroxide
46. 46.

    Which indicator is commonly used in complexometric titration with EDTA?

    Phenolphthalein Methyl orange Eriochrome Black T Ferroin
47. 47.

    In UV-Visible spectroscopy, Beer-Lambert’s law relates absorbance directly to:

    Transmittance Concentration and path length Wavelength only Refractive index
48. 48.

    The wavelength region for UV radiation in spectrophotometry is:

    100 to 200 nm 200 to 400 nm 400 to 800 nm 800 to 1000 nm
49. 49.

    Infrared (IR) spectroscopy is mainly used to identify:

    Molecular weight Functional groups Isotopic abundance Particle size
50. 50.

    Stationary phase in thin layer chromatography (TLC) is commonly:

    Alumina silicate Silica gel G Cellulose acetate Calcium carbonate
51. 51.

    Which of the following is a non-aqueous solvent used for weak base titrations?

    Water Glacial acetic acid Methanol Acetone
52. 52.

    Isoniazid is chemically specified as:

    Isonicotinic acid hydrazide Nicotinic acid amide Pyrazinamide derivative Piperazine derivative
53. 53.

    Omeprazole belongs to which chemical class?

    Benzimidazole Benzodiazepine Barbiturate Phenothiazine
54. 54.

    The IUPAC name of Paracetamol is:

    N-(4-hydroxyphenyl)acetamide 2-acetoxybenzoic acid 4-aminobenzoic acid N-acetyl-2-aminophenol
55. 55.

    Which reagent is used in the test for primary aromatic amines (Diazotization test)?

    Sodium nitrite and HCl Sodium hydroxide Silver nitrate Barium chloride
56. 56.

    Sulphonamides are structural analogues of which metabolite?

    PABA (Para-aminobenzoic acid) Folic acid Glutamic acid Methionine
57. 57.

    Kjeldahl method is used for the quantitative estimation of:

    Halogens Sulfur Nitrogen Phosphorus
58. 58.

    Which organic compound is used as a primary standard in alkalimetry?

    Sodium carbonate Potassium hydrogen phthalate Oxalic acid Sodium hydroxide
59. 59.

    Retention factor (Rf value) in chromatography is always:

    Greater than 1 Equal to zero Less than or equal to 1 Infinite
60. 60.

    NMR spectroscopy utilizes which type of radiation?

    UV rays IR rays Radio waves X-rays
61. 61.

    Which of the following is an indole alkaloid?

    Atropine Vincristine Quinine Morphine
62. 62.

    Rauwolfia serpentina belongs to which family?

    Solanaceae Apocynaceae Rubiaceae Papaveraceae
63. 63.

    The active chemical constituent of Digitalis purpurea responsible for cardiotonic activity is:

    Digitoxin Reserpine Quinine Sennoside
64. 64.

    Cinchona bark contains which major antimalarial alkaloid?

    Emetine Quinine Strychnine Piperine
65. 65.

    Sennosides present in Senna leaves belong to which chemical group?

    Anthraquinone glycosides Cardiac glycosides Saponin glycosides Flavonoid glycosides
66. 66.

    Which test is specific for the identification of Cardiac Glycosides?

    Keller-Kiliani test Borntrager test Vitali-Morin test Murexide test
67. 67.

    Borntrager’s test is used to identify:

    Anthraquinone glycosides Tropane alkaloids Flavonoids Tannins
68. 68.

    Goldbeater’s skin test is performed for the identification of:

    Alkaloids Glycosides Tannins Resins
69. 69.

    Opium is obtained from which part of Papaver somniferum?

    Unripe capsule latex Dried seeds Leaves Roots
70. 70.

    Clove contains oil whose chief chemical constituent is:

    Eugenol Cinnamaldehyde Menthol Limonene
71. 71.

    Which crude drug contains tropane alkaloids and turns purple in Vitali-Morin test?

    Datura Vinca Cinchona Nux vomica
72. 72.

    Nux vomica seeds contain which toxic alkaloid?

    Brucine Strychnine Reserpine Physostigmine
73. 73.

    Curcumin is the active coloring and medicinal component of:

    Ginger Turmeric Cinnamon Cardamom
74. 74.

    Which carbohydrate is known as Indian Gum?

    Acacia Tragacanth Agar Guar gum
75. 75.

    Which organelle or cellular structure is characterized by cystoliths in Pharmacognosy?

    Calcium oxalate crystals Calcium carbonate crystals Starch grains Aleurone grains
76. 76.

    As per Drugs and Cosmetics Act, Schedule M refers to:

    Good Manufacturing Practices (GMP) Standards for cosmetics List of prescription drugs Pack sizes of drugs
77. 77.

    Schedule H of the Drugs and Cosmetics Act deals with:

    Prescription drugs Narcotic drugs Patent and proprietary medicines Biological products
78. 78.

    Which schedule specifies requirements and guidelines for clinical trials and import of new drugs?

    Schedule Y Schedule X Schedule G Schedule U
79. 79.

    Schedule X under Drugs and Cosmetics Rules includes:

    Habit-forming and psychotropic drugs Life-saving emergency drugs Infectious vaccines Ophthalmic preparations
80. 80.

    Pharmacy Act in India was enacted in the year:

    1940 1945 1948 1955
81. 81.

    Drugs and Cosmetics Act was passed in the year:

    1940 1945 1948 1950
82. 82.

    The central pharmacy council (PCI) is reconstituted every:

    3 years 5 years 6 years 10 years
83. 83.

    Minimum educational qualification required to register as a pharmacist in India is:

    Diploma in Pharmacy (D.Pharm) Bachelor in Pharmacy (B.Pharm) Master in Pharmacy (M.Pharm) Pharm.D
84. 84.

    Education Regulations for Pharmacy course are framed by:

    Pharmacy Council of India (PCI) AICTE Ministry of Health State Pharmacy Council
85. 85.

    Which committee submitted the report in 1931 that led to the drug legislation in India?

    Chopra Committee Mudaliar Committee Bhore Committee Hathi Committee
86. 86.

    The Chairman of the Drugs Technical Advisory Board (DTAB) ex-officio is:

    Director General of Health Services (DGHS) Drugs Controller General of India President of PCI Director of Central Drugs Laboratory
87. 87.

    Central Drugs Laboratory (CDL) is located at:

    New Delhi Kolkata Mumbai Kasauli
88. 88.

    Central Research Institute (CRI) for vaccine production is situated at:

    Kasauli Lucknow Hyderabad Pune
89. 89.

    An ideal inventory control method based on annual usage value of items is:

    ABC Analysis VED Analysis EOQ Method FIFO Method
90. 90.

    In VED analysis, ‘V’ stands for:

    Vital Valuable Variable Volume
91. 91.

    Which vitamin is chemically known as Cyanocobalamin?

    Vitamin B1 Vitamin B6 Vitamin B12 Vitamin B2
92. 92.

    Deficiency of Vitamin C leads to which disease?

    Rickets Beriberi Scurvy Pellagra
93. 93.

    Which enzyme is inhibited by Allopurinol in the treatment of Gout?

    Xanthine oxidase Cyclooxygenase Carbonic anhydrase DOPA decarboxylase
94. 94.

    Which anticoagulant acts in vitro as well as in vivo?

    Warfarin Heparin Dicumarol Phenindione
95. 95.

    First pass metabolism primarily occurs in which organ?

    Kidney Liver Lungs Small intestine
96. 96.

    Which drug is an antidote for cyanide poisoning?

    Sodium nitrite and Sodium thiosulfate Atropine Pralidoxime Dimercaprol
97. 97.

    A adverse reaction caused by genetic enzyme deficiency is termed as:

    Idiosyncrasy Tachyphylaxis Tolerance Anaphylaxis
98. 98.

    Barium sulfate is used in radiography as:

    Radio-opaque contrast medium Photographic developer Diagnostic dye Antacid
99. 99.

    Megaloblastic anemia is caused by deficiency of:

    Folic acid and Vitamin B12 Iron Vitamin C Vitamin Pyridoxine
100. 100.

     Which drug causes ‘Red Man Syndrome’ as an infusion reaction?

     Vancomycin Gentamicin Ciprofloxacin Erythromycin